Treatment of acute myelocytic leukemia: a study by cancer and leukemia group B

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Treatment of acute myelocytic leukemia: a study by cancer and leukemia group B.

By Kanti R. Rai, James F. Holland, Oliver J. Glidewell, Vivian Weinberg, Kurt Brunner, J. P. Obrecht, Harvey D. Preisler, Ismat W. Nawabi, David Prager, Robert W. Carey, M. Robert Cooper, Farid Haurani, J. L. Hutchison, Richard T. Silver, Geoffrey Falkson, Peter Wiernik, H. Clark Hoagland, Clara D. Bloomfield, G. Watson James, Arlan Gottlieb, S. V. Ramanan, Johannes Blom, Nis I. Nissen, Arthur ...

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Treatment of Acute Myelocytic Leukemia : A Study by Cancer and Leukemia Group

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Second hematologic malignancies occur rarely in patients previously treated for leukemia. This report describes a patient with acute lymphoblastic leukemia who remained in complete remission for 5 yr and then developed chronic myelocytic leukemia (CML). The original lymphoblasts were associated with a partial deletion of chromosome 21, while CML was associated with a classic Philadelphia marker...

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A two-step timed sequential treatment for acute myelocytic leukemia.

Since 1980, adults with acute myelocytic leukemia (AML) have been treated on two clinical studies using intensive timed sequential therapy. All patients ages 16 to 80, including those with secondary AML (SAML) and those with AML preceded by a hematologic disorder (AHD), were treated, regardless of medical complications at the time of diagnosis. The first study combined high doses of cytarabine ...

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Clinical importance of CD7 expression in acute myelocytic leukemia. The Japan Cooperative Group of Leukemia/Lymphoma.

Forty patients (9 females and 31 males; mean age 41.9 years) with CD7+ acute myelocytic leukemia (AML) were investigated; they were classified into the following subgroups according to French-American-British classification: 15 M1, 18 M2, 3 M4, and 4 M5. Leukemic cells from all the patients were negative for T-cell-specific antigens, surface CD3, and T-cell-receptor molecules. The sex and age d...

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ژورنال

عنوان ژورنال: Blood

سال: 1981

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v58.6.1203.bloodjournal5861203